Immunoglobulin E-rheumatoid factor in the serum of patients with rheumatoid arthritis, asthma, and other diseases.

نویسندگان

  • B L Zuraw
  • C H O'Hair
  • J H Vaughan
  • D A Mathison
  • J G Curd
  • D H Katz
چکیده

A solid-phase radioimmunoassay was developed to detect immunoglobulin (Ig)E antibodies that bound to human IgG. IgE-rheumatoid factor activity was found in the serum of 18 of 20 patients with seropositive rheumatoid arthritis, 1 of 4 patients with seronegative rheumatoid arthritis, 3 of 32 patients with seronegative rheumatoid arthritis, 3 of 32 patients with asthma, and in 1 patient with hypocomplementemic vasculitis and iodide sensitivity. Immunopathologic implications of IgE-rheumatoid factor are discussed.

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عنوان ژورنال:
  • The Journal of clinical investigation

دوره 68 6  شماره 

صفحات  -

تاریخ انتشار 1981